Cathepsin Inhibitor 1( Cathepsin Inhibitor 1; Cathepsin-Inhibitor-1; CTS-IN-1 )

Catalog No. M18263 CAS No. 225120-65-0

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Product Name

Cathepsin Inhibitor 1
Note

Research use only, not for human use.
Brief Description

Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
Description

Cathepsin Inhibitor 1 is a pan-inhibitor of Cathepsin (L, L2, S, K, B).
Synonyms

Cathepsin Inhibitor 1; Cathepsin-Inhibitor-1; CTS-IN-1
Pathway

Immunology/Inflammation
Target

Antiviral
Recptor

Cathepsin K; Cathepsin L; Cathepsin L2; Cathepsin S; Cathepsin S
Research Area

Others-Field
Indication

——

CAS Number

225120-65-0
Formula Weight

401.89
Molecular Formula

C20H24ClN5O2
Purity

98%
Solubility

——
SMILES

CN1N=C(C=C1C(=O)N[C@@H](CC1=CC=CC(Cl)=C1)C(=O)NCC#N)C(C)(C)C
Chemical Name

(S)-3-(tert-butyl)-N-(3-(3-chlorophenyl)-1-((cyanomethyl)amino)-1-oxopropan-2-yl)-1-methyl-1H-pyrazole-5-carboxamide

1. Asaad N, et al. Bioorg Med Chem Lett, 2009, 19(15), 4280-4283.

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